Lecture slides 2024

Day 1

Welcome and practical information (TR)

Sequencing and applications (TR)

Fundamentals of molecular biology 1: A guided tour of the (human) genome (RS)

Fundamentals of molecular biology 2: From DNA to biological function (RS)

Fundamentals of molecular biology 3: Genomics in biomedical research (RS)

Illumina sequencing technology (AS)

PacBio sequencing technology (ATK)

Day 2

Introduction to Nanopore sequencing (TH)

Library preparation (AS)

Experimental design (AS)

Basic file formats (AS)

Access to computational resources (TR)

Day 3

Data preprocessing (AS): Exercises

Introduction to containers (AS)

Introduction to analysis pipelines with Nextflow (AS)

Introduction to Snakemake (EBB)

Day 4 and 5

De novo genome assembly (KL) Part 1, Part 2, Part 3, Part 4, Exercises

Day 6

Introduction to variant calling (BS): Exercises Answers

Human germline variant calling (YS)

Day 7

Somatic variant calling and interpretation in the context of cancer (SN)

Day 8

Microbiome sequencing and analysis (NKN)

Multi-omic network analysis (NKN)

Day 9

Introduction to RNA-Seq (AS)

Small RNA transcriptomics (TBR): Exercises

Day 10

Machine learning in computational biology (MP)